Publications
Rather than using this static list, I’d encourage you to visit my Google
Scholar page, which I keep updated automatically.
Publications are in reverse chronological order with all types of submissions listed together. As time permits, I will reorganize this and will be adding links to the associated papers, talks, posters, etc.
- Owen M, Shevell M, Donofrio M, Majnemer A, McCarter R, Vezina G, Bouyssi-Kobar M, Evangelou I, Freeman D, Weisenfeld N, Limperopoulos C. Brain Volume and Neurobehavior in Newborns with Complex Congenital Heart Defects. J Pediatr. 2013 Dec 21.
- McAnulty G, Duffy FH, Kosta S, Weisenfeld NI, Warfield SK, Butler SC, Alidoost M, Bernstein JH, Robertson R, Zurakowski D, Als H. School-age effects of the newborn individualized developmental care and assessment program for preterm infants with intrauterine growth restriction: preliminary findings. BMC Pediatr. 2013 Feb 19;13:25.
- Weisenfeld NI, Peters JM, Tsai PT, Prabhu SP, Dies KA, Sahin M, Warfield SK. A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. Pediatr Neurol. 2013 Feb;48(2):105-10.
- Als H, Duffy FH, McAnulty G, Butler SC, Lightbody L, Kosta S, Weisenfeld NI, Robertson R, Parad RB, Ringer SA, Blickman JG, Zurakowski D, Warfield SK. NIDCAP improves brain function and structure in preterm infants with severe intrauterine growth restriction. J Perinatol. 2012 Oct;32(10):797-803.
- Weisenfeld NI and Warfield SK. Learning likelihoods for labeling (L3): a general multi-classifier segmentation algorithm. To appear in MICCAI, 2011.
This work is a generalization of the segmentation strategy that I developed for newborn segmentation (see NeuroImage, 2009, paper below). The new algorithm unifies label fusion and statistical classification.
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- A. Hans, N. Weisenfeld, M. Alexiuk, J. Saunders, E. Liebenthal, A. Wittek, G. Joldes, K. Miller, S. Warfield. Comparison of registration algorithms for capturing intraoperative brain shift. In Human Brain Mapping, Proceedings, 2011. poster to be presented.
In this work with Arne Hans, we address the problem of registration validation and apply our solution to the evaluation of several registration algorithms for capturing "brain shift" during neurosurgery. The key problem is: how do you design a metric that is good for assessing registration accuracy, and therefore image overlap, but is not related to the registration metric used.
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- N. I. Weisenfeld and S. K. Warfield. softSTAPLE: Truth and Performance Level Estimation from Probabilistic Segmentations. In IEEE Int'l Symposium on Biomedical Imaging: ISBI, Proceedings, 2011. paper read March 3rd, 2011.
This is one of my key projects and relates to my recent segmentation work. In short, we've developed a new version of the STAPLE algorithm that operates on probabilistic inputs, rather than label maps. That is, instead of observing a label at each voxel from each rater, we observe the probability of every label. This allows us to feed the output of STAPLE back into STAPLE in order to, for instance, separately assess both inter- and intra- individual variability. This also allows us to "fuse" the output of probabilistic classifiers.
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- A. Hans, A. Wittek, K. Miller, N. I. Weisenfeld, M. Alexiuk, E. Liebenthal, G. R. Sutherland, and S. K. Warfield. Improved visualization of brain anatomy and func- tion, for surgery, through real-time non-rigid registration. In International Society for Magnetic Resonance in Medicine: ISMRM, 2011. poster to be presented May 7–13, 2011 in Montréal.
- N. I. Weisenfeld. Segmentation and Atlas Construction for the Analysis of Newborn Brain MRI. Doctoral dissertation in cognitive and neural systems, Boston University, 2010.
- N.I. Weisenfeld and S.K. Warfield. A data-driven approach to discovering common brain anatomy. In Biomedical Imaging: From Nano to Macro, 2009. ISBI ’09. IEEE International Symposium on, pages 217–220, 28 2009-July 1 2009
- Neil I Weisenfeld and Simon K Warfield. Automatic segmentation of newborn brain MRI. Neuroimage, 47(2):564–72, Aug 2009.
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- M. Krishnan, O. Commowick, S. S. Jeste, N. Weisenfeld, A. Hans, M. Gregas, M. Sahin, and S. K. Warfield. Diffusion features of white matter in tuberous sclerosis complex assessed with tractography. Pediatric Neurology, in press, 2009.
- L.J. Woodward, C. Spencer, N.I. Weisenfeld, R. Watts, and S.K. Warfield. Prenatal methadone exposure and infant neuroanatomical outcomes: Does dose matter? In Pediatric Academic Societies Meeting, 2008. Poster 4455.13 presented at poster session “Neonatology.” Conference held in Honolulu, Hawaii, May 2–6, 2008.
- S.K. Warfield, N.I. Weisenfeld, C. Spencer, and L.J. Woodward. Prenatal exposure to methadone reduces brain tissue volumes. In Pediatric Academic Societies Meeting, 2008. Poster 5370.10 presented at symposium “Neurology: neonatal and pediatric.” Conference held in Honolulu, Hawaii, May 2–6, 2008.
- N.I. Weisenfeld and S.K. Warfield. Simultaneous alignment and central tendency estimation. In Statistical Registration: Pair-Wise and Group-Wise Alignment and Atlas Formation: Workshop at MICCAI 2007, October 2007. Oral presentation at workshop held in conjunction with Medical Image Computing and Computer Assisted Intervention (MICCAI) 2007 in Brisbane, Australia.
- N.I. Weisenfeld, A.U.J. Mewes, and S.K. Warfield. Segmentation of newborn brain MRI. In International Symposium on Biomedical Imaging, pages 766–769. IEEE, April 2006.
- Neil I. Weisenfeld, Andrea U. J. Mewes, and Simon K. Warfield. Highly accurate seg- mentation of brain tissue and subcortical gray matter from newborn MRI. In Larsen, R and Nielsen, M and Sporring, J, editor, MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI 2006, PT 1, volume 4190 of LECTURE NOTES IN COMPUTER SCIENCE, pages 199–206, 2006. 9th Interna- tional Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2006), Copenhagen, DENMARK, OCT 01-06, 2006.
- SK Warfield, SJ Haker, IF Talos, CA Kemper, N Weisenfeld, AUJ Mewes, D Goldberg- Zimring, KH Zou, CF Westin, WM Wells, CMC Tempany, A Golby, PM Black, FA Jolesz, and R Kikinis. Capturing intraoperative deformations: research experi- ence at Brigham and Women’s Hospital. MEDICAL IMAGE ANALYSIS, 9(2):145– 162, APR 2005. International Symposium on Surgery Simulation and Soft Tissue Modeling, JUAN LES PINS, FRANCE, JUN 12-13, 2003.
- N.I. Weisenfeld and S.K. Warfield. Normalization of joint image-intensity statistics in MRI using the Kullback-Leibler divergence. In International Symposium on Biomedical Imaging, Arlington, VA, April 15–18 2004. IEEE.
- M. De Craene, A. du Bois d’ Aische, B. Macq, F. Kipfmueller, N. Weisenfeld, S. Haker, and S.K. Warfield. Multi-modeal non-rigid registration using a stochastic gradient approximation. In International Symposium on Biomedical Imaging, Arlington, VA, April 15–18 2004. IEEE.
- A.D. d’Aische, M. De Craene, S. Haker, N. Weisenfeld, C. Tempany, B. Macq, and S.K. Warfield. Improved non-rigid registration of prostate MRI. In Barillot, C and Haynor, DR and Hellier, P, editor, MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI 2004, PT 1, PROCEEDINGS, volume 3216, Part 1 of LECTURE NOTES IN COMPUTER SCIENCE, pages 845– 852, 2004. 7th International Conference on Medical Image Computing and Computer- Assisted Intervention (MICCAI 2004), St Malo, FRANCE, SEP 26-29, 2004.
- N.I. Weisenfeld. A non-contact active stereo imaging system for intraoperative surface measurements. Master’s thesis, Massachusetts Institute of Technology, Cambridge MA USA, May 2002.
- LD Gugino, JR Romero, L Aglio, D Titone, M Ramirez, A Pascual-Leone, E Grimson, N Weisenfeld, R Kikinis, and ME Shenton. Transcranial magnetic stimulation coreg- istered with MRI: a comparison of a guided versus blind stimulation technique and its effect on evoked compound muscle action potentials. CLINICAL NEUROPHYSIOL- OGY, 112(10):1781–1792, OCT 2001.
- R. Kikinis, N.R. Mehta, A. Nabavi, E. Chatzidakis, S. Warfield, D. Gering, N. Weisenfeld, R.S. Pergolizzi, R.B. Scwarz, N. Hata, W. Wells, E. Grimson, Black P.M., and F.A. Jolesz. Intraoperative visualization. In Mazziotta J.C., Toga A.W., and Frackowiak R.S.J., editors, Brain Mapping: The Disorders, 2nd ed., pages 107–129. Academic Press, San Diego, CA, USA, 2000.
- CM Adler, I Elman, N Weisenfeld, L Kestler, D Pickar, and A Breier. Effects of acute metabolic stress on striatal dopamine release in healthy volunteers. SCHIZOPHRENIA RESEARCH, 41(1, Sp. Iss. SI):A247, JAN 3 2000.
- CM Adler, I Elman, N Weisenfeld, L Kestler, D Pickar, and A Breier. Effects of acute metabolic stress on striatal dopamine release in healthy volunteers. NEUROPSY- CHOPHARMACOLOGY, 22(5):545–550, MAY 2000
- I. Elman, L. Sokoloff, C.M. Adler, N. Weisenfeld, and A. Breier. The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers. BRAIN RESEARCH, 815(2):243–249, JAN 9 1999.
- A Breier, TP Su, AK Malhotra, I Elman, CM Adler, NI Weisenfeld, and D Pickar. Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders. NEUROPSYCHOPHARMA- COLOGY, 20(4):340–345, APR 1999
- CM Adler, I Elman, N Weisenfeld, L Kesstler, D Pickar, and A Breier. Effects of 2- deoxyglucose-induced glucoprivation on striatal dopamine release in healthy volunteers. BIOLOGICAL PSYCHIATRY, 45(8, Suppl. S):349, APR 15 1999.
- A. Nabavi, N. Hata, E. Chatzidakis, M. Leventon, N. Weisenfeld, R.S. Pergolizzi, K. Oge, P.M. Black, F.A. Jolesz, and R. Kikinis. Image guided neurosurgery: Visual- ization of brain shift. In U. Spetzger, S. Stiehl, and J. M. Gilsbach, editors, Navigated Brain Surgery, pages 17–26. Verlag Mainz, Aachen, Germany, 1998.
- A Breier, L Kestler, C Adler, I Elman, N Wiesenfeld, A Malhotra, and D Pickar. Dopamine D2 receptor density and personal detachment in healthy subjects. Am J Psychiatry, 155(10):1440–1442, Oct 1998.
- A Breier, CM Adler, N Weisenfeld, TP Su, I Elman, L Picken, AK Malhotra, and D Pickar. Effects of NMDA antagonism on striatal dopamine release in healthy subjects: Application of a novel PET approach. SYNAPSE, 29(2):142–147, JUN 1998.
- A Breier, TP Su, R Saunders, RE Carson, BS Kolachana, N Weisenfeld, AK Malhotra, I Elman, WC Eckelman, and D Pickar. Assessment of synaptic dopamine concentra- tions in schizophrenia with PET. SCHIZOPHRENIA RESEARCH, 24(1-2):176, MAR 1997.
- A Breier, TP Su, R Saunders, RE Carson, BS Kolachana, A deBartolomeis, DR Wein- berger, N Weisenfeld, AK Malhotra, WC Eckelman, and D Pickar. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Ev- idence from a novel positron emission tomography method. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 94(6):2569–2574, MAR 18 1997.
- A Breier, AK Malhotra, DA Pinals, NI Weisenfeld, and D Pickar. Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers. AMERICAN JOURNAL OF PSYCHIATRY, 154(6):805–811, JUN 1997
- AK Malhotra, DA Pinals, N Weisenfeld, D Pickar, and A Breier. NMDA receptor function and schizophrenia: Studies with ketamine. BIOLOGICAL PSYCHIATRY, 39(7):296, APR 1 1996.
- A Breier, TP Su, N Weisenfeld, I Elman, C Adler, AK Malhotra, and D Pickar. Assessment of striatal dopamine function in schizophrenia. BIOLOGICAL PSYCHIATRY, 39(7):48, APR 1 1996.
- C.A. Johnson, N.I. Weisenfeld, B.L. Trus, J.F. Conway, R.L. Martino, and A.C. Steven. Orientation determination in the 3D reconstruction of icosahedral viruses using a par- allel computer. In Proceedings Supercomputing ’94, pages 550–559 and 817. IEEE Computer Society, 1994.